Dental surgeons, maxillofacial surgeons and implantologists are increasingly interested in the effects of vitamin D on bone metabolism and the immune system. The correct concentration of this prohormone potentially correlates with success at each stage of osteointegration of endosseous implants.‪A review of literature related to the topic of the paper.‬‪A suitable level of vitamin D3 is crucial from the day of surgery. It influences the modulation of the immune system – increases the production of cathelicidin and defensin, and reduces the expression of proinflammatory cytokines. It also has a positive effect on bone metabolism in osteo-suppression via the induction of osteoblasts and osteoclasts and continuous bone remodeling around the implant after prosthetic restoration.‪The prevalence of low vitamin D levels in the European population leads to the conclusion that a high deficit is not a factor directly responsible for failures in the process of osteointegration.



Author ORCID Identifier

Grzegorz Trybek https://orcid.org/0000-0002-3900-4901