Background: Diseases of genetic origin are very often associated with oral disorders. One of them is Gardner syndrome (GS) a rare variant of familial adenomatous polyposis (FAP), whose main manifestation is colon cancer. Its most common oral cavity symptoms include osteomas, odontomas and impacted or supernumerary teeth. Material and methods: Medline (PubMed), Medline (Ebsco), Scopus and Google Scholar databases were searched oral manifestations of Gardner Syndrome.Results: Thirty-eight articles met inclusion criteria. The most frequently mentioned oral changes included osteomas, impacted teeth, supernumerary teeth and odontomas. Conclusion: This review provides evidence for associating FAP with oral disorders. Dentists can be the first doctor able to diagnose Gardner Syndrome and refer patients for systemic treatment. The incidence of changes in the oral cavity is significant and should be considered as an indication of Gardner Syndrome.



Author ORCID Identifier

Olga Preuss https://orcid.org/0000-0002-9744-8885; Aleksandra Jaron https://orcid.org/0000-0001-7727-6388; Anna Grzywacz https://orcid.org/0000-0002-2633-520X; Grzegorz Trybek https://orcid.org/0000-0002-3900-4901

Creative Commons License

Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.