Background: The aim is to identify novel methods and demand in using amber and its products in the field of medicine, health preservation and medical tourism. Material and methods: Quantitative and qualitative analysis is done on patents and patent applications indicating the use of natural amber and its derivatives as reflected in the title and/or abstract sections. Data is analyzed by 4 dimensions: temporal, sectoral, territorial, institutional. The study period covers 1975-2020. Data source is the Dimensions patents database. Results: The development of technologies for using or processing amber and its derivatives is characterized by low and unstable patent activity. The majority of patents are generated at the regions with amber deposits. Wellness specialization is found to be an important technology driver, although outperformed by jewelry production and processing technologies. The WIPO plays a significant role in protecting the amber related innovations in wellness. Conclusions: The patenting activity for amber processing technologies is low, including in the field of medicine, health preservation and medical tourism. Cross-border networking between Russia (primarily the Kaliningrad region), Poland, Lithuania, and Germany can positively affect the development of Baltic amber cluster, boosting the demand for high-tech processing of amber and expanding its application in wellness.