Purslane supplementation lowers oxidative stress, inflammatory and muscle damage biomarkers after high-intensity intermittent exercise in female runners

Authors

Anis Charkhi Sahl Abad, Department of Exercise Physiology, Faculty of Physical Education and Sport Sciences, University of Tehran, Tehran, IranFollow
Amine Ghram, Department of Exercise Physiology, Faculty of Physical Education and Sport Sciences, University of Tehran, Tehran, Iran; Department of Cardiac Rehabilitation, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, IranFollow
Rahman Soori, Department of Exercise Physiology, Faculty of Physical Education and Sport Sciences, University of Tehran, Tehran, IranFollow
Ali Akbarnejad, Department of Exercise Physiology, Faculty of Physical Education and Sport Sciences, University of Tehran, Tehran, IranFollow
Fatemeh Azizi Ghuchan, Department of Exercise Physiology, Bojnourd Branch, Islamic Azad University, Bojnourd, IranFollow
Mohammad Mehdi Zare, 1 Department of Exercise Physiology, Faculty of Physical Education and Sport Sciences, University of Tehran, Tehran, IranFollow
Anthony C. Hackney, Department of Exercise & Sport Science, University of North Carolina, Chapel Hill, NC, USAFollow
Stephen J. Bailey, School of Sport, Exercise and Health Sciences, Loughborough University, Loughborough, United KingdomFollow

Abstract

Background: The aim of this study was to determine the effect of purslane supplementation on oxidative stress, inflammation and muscle damage biomarkers after completing high-intensity interval exercise (HIIE). Methods: Nine healthy female runners completed a HIIE treadmill protocol comprising 1 min at 100% of the peak treadmill velocity attained in a preliminary exhaustive incremental treadmill test, interspersed by 1 min of passive recovery, until they had run for 2.5 km. Athletes repeated this test following 10 days of supplementation with 1000 mg per day of purslane. Results: At baseline (i.e., absence of purslane supplementation) the HIIE protocol increased 9-HODE (p < 0.001), 13-HODE (p < 0.001), IL-17 (p < 0.001), TNF-α (p < 0.001), and LDH (p < 0.001). After purslane consumption, resting 9-HODE, 13-HODE, IL-17, TNF-α, and LDH were lowered (p < 0.001) and IL-10 was increased (p < 0.001) compared to before purslane supplementation. After purslane consumption and following the HIIE protocol, the responses of these biomarkers were lower compared to baseline (p < 0.001). Conclusion: Ten days of purslane supplementation blunted the perturbation to biomarkers of oxidative stress, inflammation and muscle damage in female runners completing a HIIE protocol.

Recommended Citation

Charkhi Sahl Abad A, Ghram A, Soori R, Akbarnejad A, Azizi Ghuchan F, Zare MM, Hackney AC, Bailey SJ. Purslane supplementation lowers oxidative stress, inflammatory and muscle damage biomarkers after high-intensity intermittent exercise in female runners. Balt J Health Phys Act. 2021;13(1):17-27. doi: 10.29359/BJHPA.13.1.03

DOI

10.29359/BJHPA.13.1.03

Author ORCID Identifier

Anthony C. Hackney ORCID 0000-0002-6607-1472; Stephen J. Baile ORCID 0000-0003-0923-6362

Creative Commons License

This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.