Background: The aim of this study was to determine the effect of purslane supplementation on oxidative stress, inflammation and muscle damage biomarkers after completing high-intensity interval exercise (HIIE). Methods: Nine healthy female runners completed a HIIE treadmill protocol comprising 1 min at 100% of the peak treadmill velocity attained in a preliminary exhaustive incremental treadmill test, interspersed by 1 min of passive recovery, until they had run for 2.5 km. Athletes repeated this test following 10 days of supplementation with 1000 mg per day of purslane. Results: At baseline (i.e., absence of purslane supplementation) the HIIE protocol increased 9-HODE (p < 0.001), 13-HODE (p < 0.001), IL-17 (p < 0.001), TNF-α (p < 0.001), and LDH (p < 0.001). After purslane consumption, resting 9-HODE, 13-HODE, IL-17, TNF-α, and LDH were lowered (p < 0.001) and IL-10 was increased (p < 0.001) compared to before purslane supplementation. After purslane consumption and following the HIIE protocol, the responses of these biomarkers were lower compared to baseline (p < 0.001). Conclusion: Ten days of purslane supplementation blunted the perturbation to biomarkers of oxidative stress, inflammation and muscle damage in female runners completing a HIIE protocol.
Charkhi Sahl Abad A, Ghram A, Soori R, Akbarnejad A, Azizi Ghuchan F, Zare MM, Hackney AC, Bailey SJ. Purslane supplementation lowers oxidative stress, inflammatory and muscle damage biomarkers after high-intensity intermittent exercise in female runners. Balt J Health Phys Act. 2021;13(1):17-27. doi: 10.29359/BJHPA.13.1.03
Author ORCID Identifier
Anthony C. Hackney ORCID 0000-0002-6607-1472; Stephen J. Baile ORCID 0000-0003-0923-6362