The present study aimed to gain knowledge about the diversity of factors determining physical activity in youth from the V4 countries. The study involved 2145 students aged 15-17 years from the Visegrad countries (V4): the Czech Republic, Slovakia, Hungary and Poland. A diagnostic survey was used as the research method in the form of the International Physical Activity Questionnaire (IPAQ-L). The Kruskall-Wallis and Mann-Whitney U tests as well as the Pearson Chi-square independence test were applied to do the statistical calculations and determine statistically significant relationships. More than half of the surveyed youth from the V4 countries (58.2%) demonstrated a high level of physical activity. Fewer than 6% of the adolescents exhibited a low level of physical activity. Young people tend to exhibit a high PA level, with significantly higher values visible in boys, and the WHO health recommendations were met by 84% of the respondents. The main factors determining the level of physical activity, beside sex, were age and self assessment of physical fitness.